- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
GIT1 Antibody / p95-APP1 (F54926)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54926-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54926-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity purified |
| UniProt | Q9Y2X7 |
| Localization | Cytoplasmic |
| Applications | Western blot : 1:500-1:1000 Flow cytometry : 1:50-1:100 (1x10e6 cells) |
| Limitations | This GIT1 antibody is available for research use only. |
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GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine-phosphorylated paxillin in cytoplasmic complexes (from SwissProt).
The stated application concentrations are suggested starting points. Titration of the GIT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 533-561 from the human protein was used as the immunogen for the GIT1 antibody.
Aliquot the GIT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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