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- Tel: 858.663.9055
- Email: info@nsjbio.com
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GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. Cross-linking experiments have shown that GFRP is usually expressed as a homodimer or pentamer.
Optimal dilution of the GFRP antibody should be determined by the researcher.
A recombinant fragment of human protein was used as the immunogen for the GCHFR antibody.
Aliquot the GFRP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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