- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Titration of the G3BP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 401-430 from the human protein was used as the immunogen for this G3BP1 antibody.
Aliquot the G3BP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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