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Home >> Antibodies >> FGFR1 Antibody / Fibroblast growth factor receptor 1

FGFR1 Antibody / Fibroblast growth factor receptor 1 (R32578)

  Catalog No Formulation Size Price (USD)  
Image R32578 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human HepG2 cell lysate with FGFR1 antibody at 0.5ug/ml. Predicted molecular weight: 75-160 kDa depending on glycosylation level
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P11362
Applications Western blot : 0.5-1ug/ml
Limitations This FGFR1 antibody is available for research use only.
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Description

FGFR1, Fibroblast growth factor receptor 1, also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. The FGFR1 gene is localized to 8p12-p11.2 by in situ hybridization. FGFR1 is essential for the normal formation of the organ of Corti and that phenotype severity observed in FGFR1 mutants is dependent on the dose of FGFR1. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome 2.

Application Notes

Optimal dilution of the FGFR1 antibody should be determined by the researcher.

Immunogen

Amino acids 489-520 (FGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDA-human) were used as the immunogen for the FGFR1 antibody.

Storage

After reconstitution, the FGFR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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