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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Feline sarcoma oncogene is an enzyme that in humans is encoded by the FES gene. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. Non-onc intervening sequences were present in the human counterpart. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia, but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.
Optimal dilution of the FES antibody should be determined by the researcher.
Amino acids RQQLRKTYSEQWQQLQQELTKTHSQDIEKLK from the human protein were used as the immunogen for the FES antibody.
After reconstitution, the FES antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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