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Home >> Antibodies >> ER Antibody / Estrogen Receptor alpha PE Conjugate

ER Antibody / Estrogen Receptor alpha PE Conjugate [clone NR3Ga-3] (V7061PE)

  Catalog No Formulation Size Price (USD)  
Image V7061PE-100T 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 Tests 519
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Intracellular FACS testing of human MCF-7 cells: Black=cells alone; Green=isotype control; Red=ER antibody
Availability 1-3 business days
Species Reactivity Human. Other species not known.
Format PE Conjugate
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name NR3Ga-3
Purity Protein G affinity chromatography
Buffer 1X PBS, pH 7.4
Gene ID 2099 (Human)
Localization Intracellular, Nuclear
Applications Flow Cytometry : 5ul/test/million cells or 5ul/test/100ul of whole blood
Limitations This ER antibody is available for research use only.
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Description

This antibody is specific to estrogen receptor (ER) alpha and shows minimal cross-reaction with other members of the family. Estrogen receptor is an important regulator of growth and differentiation in the mammary gland. Presence of estrogen receptor in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Immunogen

Recombinant human ER alpha protein (aa 2-185) was used as the immunogen for this antibody.

Storage

Store the ER antibody at 2-8°C. Conjugate is light sensitive, store in the dark.

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