- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ENPP2 Antibody / Autotaxin (F54782)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54782-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F54782-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | Q13822 |
| Applications | Flow cytometry : 1:25 (1x10e6 cells) Western blot : 1:500-1:1000 Immunohistochemistry (FFPE) : 1:25 |
| Limitations | This ENPP2 antibody is available for research use only. |
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ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. This protein is secreted and further processed to make the biologically active form.
The stated application concentrations are suggested starting points. Titration of the ENPP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 401-430 from the human protein was used as the immunogen for the ENPP2 antibody.
Aliquot the ENPP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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