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Home >> Antibodies >> EED Antibody

EED Antibody (R31834)

  Catalog No Formulation Size Price (USD)  
Image R31834 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat heart, 2) rat kidney, 3) rat liver, 4) rat lung, and 5) human SKOV lysate with EED antibody. Multiple isoforms can be observed from 30~65 kDa.
Availability 1-3 business days
Species Reactivity Human, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt O75530
Applications Western blot : 0.1-0.5ug/ml
Limitations This EED antibody is available for research use only.
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Description

Polycomb protein EED is a protein that in humans is encoded by the EED gene. It is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta-7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. Furthermore, this protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Application Notes

Optimal dilution of the EED antibody should be determined by the researcher.

Immunogen

Amino acids 256-441 of human EED were used as the immunogen for the EED antibody.

Storage

After reconstitution, the EED antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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