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Home >> Antibodies >> EED Antibody

EED Antibody (F53258)

  Catalog No Formulation Size Price (USD)  
Image F53258-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F53258-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Western blot testing of EED antibody at 1:1000 dilution + mouse brain lysate; Predicted molecular weight: 50 kDa (isoform 1), 53 kDa (isoform 2), 46 kDa (isoform 3).
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt O75530
Applications Western blot : 1:1000
Limitations This EED antibody is available for research use only.
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Description

Polycomb protein EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin β7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene. [Wiki]

Application Notes

Titration of the EED antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This EED antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 38-72 amino acids from the N-terminal region of human EED.

Storage

Aliquot the EED antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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