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Home >> Antibodies >> Desmoplakin Antibody / DSP

Desmoplakin Antibody / DSP (RQ4353)

  Catalog No Formulation Size Price (USD)  
Image RQ4353 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human HepG2 cell lysate with Desmoplakin antibody at 0.5ug/ml. Predicted molecular weight: ~332 kDa (isoform DPI), ~260 kDa (isoform DPII), ~279 kDa (isoform DPIa).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P15924
Applications Western blot : 0.5-1ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This Desmoplakin antibody is available for research use only.
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Description

Desmoplakin is a protein in humans that is encoded by the DSP gene. This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the Desmoplakin antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids Q1810-A2092 was used as the immunogen for the Desmoplakin antibody.

Storage

After reconstitution, the Desmoplakin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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