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- Tel: 858.663.9055
- Email: info@nsjbio.com
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene.
The stated application concentrations are suggested starting points. Titration of the DcR3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 22-48 from the human protein was used as the immunogen for the DcR3 antibody.
Aliquot the DcR3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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