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- Email: info@nsjbio.com
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Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. The enzyme also hydroxylates etoposide.
Optimal dilution of the CYP3A4 antibody should be determined by the researcher.
A synthetic peptide specific to human Cytochrome P450 3A4 / CYP3A4 was used as the immunogen for the CYP3A4 antibody.
Store the CYP3A4 antibody at -20oC.
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