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Home >> Antibodies >> CYP1A1/1A2 Antibody

CYP1A1/1A2 Antibody [clone MC1] (V7709)

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  Catalog No Formulation Size Price (USD)  
Image V7709-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7709-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7709SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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SDS-PAGE analysis of purified, BSA-free CYP1A1/1A2 antibody (clone MC1) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free CYP1A1/1A2 antibody (clone MC1) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name MC1
Purity Protein G affinity chromatography
UniProt P04798
Applications Immunofluorescence : 1-2ug/ml
Western blot : 1-2ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This CYP1A1/1A2 antibody is available for research use only.
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Description

Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.

Application Notes

Optimal dilution of the CYP1A1/1A2 antibody should be determined by the researcher.

Immunogen

3-methylcholanthrene induced rat cytochrome P450 protein was used as the immunogen for the CYP1A1/1A2 antibody.

Storage

Store the CYP1A1/1A2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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