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- Tel: 858.663.9055
- Email: info@nsjbio.com
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.
The stated application concentrations are suggested starting points. Titration of the CYP11B2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 120-147 from the human protein was used as the immunogen for the CYP11B2 antibody.
Aliquot the CYP11B2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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