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Home >> Antibodies >> CTSD Antibody / Cathepsin D

CTSD Antibody / Cathepsin D [clone CEF-3] (RQ5176)

  Catalog No Formulation Size Price (USD)  
Image RQ5176 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human 1) MCF7 and 2) SK-BR-3 cell lysate with CTSD antibody. Expected molecular weight: 43-46 kDa and 28 kDa (heavy chain).
IHC staining of FFPE human ovarian cancer with CTSD antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name CEF-3
Purity Affinity purified
UniProt P07339
Applications Western blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:50-1:200
Limitations This CTSD antibody is available for research use only.
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Description

Cathepsin D / CTSD is an acid protease active in intracellular protein breakdown. Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Application Notes

Optimal dilution of the CTSD antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Cathepsin D / CTSD was used as the immunogen for the CTSD antibody.

Storage

Store the CTSD antibody at -20oC.

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