- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Cdk2 Antibody (R30623)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R30623 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| UniProt | P24941 |
| Applications | Western blot : 0.5-1ug/ml |
| Limitations | This Cdk2 antibody is available for research use only. |
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Cyclin-Dependent Kinase 2 is also know as p33. The protein is highly homologous to p34 (CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting thatCdk2is the human homolog of Eg1. The gene is mapped to 12q13, the same region to which theCdk4gene maps. Human Cyclin A binds independently to two kinases, p34/Cdc2) or p33/Cdk2. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/Cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65% sequence identity with p34(cdc2). Cdk2 plays a unique role in cell cycle regulation of vertebrate cells.
The stated application concentrations are suggested starting amounts. Titration of the Cdk2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Amino acids 277-298 (AKAALAHPFFQDVTKPVPHLRL) were used as the immunogen for this Cdk2 antibody (100% homologous in human, mouse and rat).
After reconstitution, the Cdk2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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