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Home >> Antibodies >> CDC25C Antibody

CDC25C Antibody (R32056)

  Catalog No Formulation Size Price (USD)  
Image R32056 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat ovary, 2) rat liver, 3) human HeLa, 4) human SW620 lyate with CDC25C antibody. Expected molecular weight: ~53/60 kDa (unmodified/phosphorylated).
Availability 1-3 business days
Species Reactivity Human, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P30307
Applications Western blot : 0.1-0.5ug/ml
Limitations This CDC25C antibody is available for research use only.
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Description

M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Application Notes

Optimal dilution of the CDC25C antibody should be determined by the researcher.

Immunogen

Amino acids 175-473 of human CDC25C were used as the immunogen for the CDC25C antibody.

Storage

After reconstitution, the CDC25C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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