- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD59 Antibody (Center Region) (F54091)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54091-0.05ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.05 ml | 185 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | P13987 |
| Applications | Western Blot : 1:2000 |
| Limitations | This CD59 antibody is available for research use only. |
|
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Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. [UniProt]
The stated application concentrations are suggested starting points. Titration of the CD59 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 74-110 from human CD59 was used as the immunogen for the CD59 antibody.
Aliquot the CD59 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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