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Home >> Antibodies >> CD27 Antibody

CD27 Antibody [clone 203.6] (V2986)

  Catalog No Formulation Size Price (USD)  
Image V2986-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2986-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2986SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG3, kappa
Clone Name 203.6
Purity Protein G affinity chromatography
UniProt P26842
Localization Cell surface
Applications Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Limitations This CD27 antibody is available for research use only.
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Description

Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis.

Application Notes

Optimal dilution of the CD27 antibody should be determined by the researcher.

Immunogen

Sezary cells were used as the immunogen for the CD27 antibody.

Storage

Store the CD27 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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