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- Tel: 858.663.9055
- Email: info@nsjbio.com
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This mAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi s sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Optimal dilution of the CD117 antibody should be determined by the researcher.
Recombinant full-length human protein was used as the immunogen for the CD117 antibody.
Aliquot the CD117 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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