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Home >> Antibodies >> CD10 Antibody / Neprilysin

CD10 Antibody / Neprilysin [clone 307CT12.12.5] (F53573)

  Catalog No Formulation Size Price (USD)  
Image F53573-0.1ML In ascites with 0.09% sodium azide 0.1 ml 399
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CD10 antibody western blot analysis in CEM lysate.
Availability 1-3 business days
Species Reactivity Human
Format Ascites
Clonality Monoclonal (mouse origin)
Isotype Mouse IgM
Clone Name 307CT12.12.5
Purity Ascites
UniProt P08473
Localization Cell surface, Cytoplasmic
Applications Western blot : 1:1000-1:4000
Limitations This CD10 antibody is available for research use only.
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Description

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. [UniProt]

Application Notes

Titration of the CD10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 272-300 from the human protein was used as the immunogen for this CD10 antibody.

Storage

Aliquot the CD10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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