• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> CCN1 Antibody

CCN1 Antibody (R31792)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image R31792 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 419
Bulk quote request
Western blot testing of 1) rat thymus, 2) rat skeletal muscle, 3) human A431, 4) SGC, 5) 22RV1 lysate with CCN1 antibody. Predicted/observed molecular weight ~42 kDa.
Western blot testing of 1) rat thymus, 2) rat skeletal muscle, 3) human A431, 4) SGC, 5) 22RV1 lysate with CCN1 antibody. Predicted/observed molecular weight ~42 kDa.
Availability 1-3 business days
Species Reactivity Human, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt O00622
Applications Western blot : 0.1-0.5ug/ml
Limitations This CCN1 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Description

Cysteine-rich angiogenic inducer 61 (CYR61) or CCN family member 1 (CCN1), is a matricellular protein that in humans is encoded by the CYR61 gene. CYR61 is a secreted, extracellular matrix (ECM)-associated signaling protein of the CCN family (CCN intercellular signaling protein). And it is capable of regulating a broad range of cellular activities, including cell adhesion, migration, proliferation, differentiation, apoptosis, and senescence through interaction with cell surface integrin receptors and heparan sulfate proteoglycans. During embryonic development, CYR61 is critical for cardiac septal morphogenesis, blood vessel formation in placenta, and vascular integrity. In adulthood CYR61 plays important roles in inflammation and tissue repair, and is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Application Notes

Optimal dilution of the CCN1 antibody should be determined by the researcher.

Immunogen

Amino acids 54-381 of human CCN1 were used as the immunogen for the CCN1 antibody.

Storage

After reconstitution, the CCN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all CCN1 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.