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Home >> Antibodies >> Caspase-7 Antibody

Caspase-7 Antibody (R30514)

  Catalog No Formulation Size Price (USD)  
Image R30514 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of Caspase-7 antibody and Lane 1: HeLa; 2: MCF-7; 3: rat liver; 4: rat kidney lysate. Expected/observed molecular weight ~34 kDa (full length).
IHC-P: Caspase-7 antibody testing of human intestinal cancer tissue. HIER: steamed with pH6 citrate buffer.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P55210
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 0.5-1ug/ml
Limitations This Caspase-7 antibody is available for research use only.
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Description

Caspase-7 is a human protein encoded by the CASP7 gene. Orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the cysteine aspartate protease family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of the protein regulates microglia activation through a protein kinase C-delta (PRKCD)-dependent pathway.

Application Notes

The stated application concentrations are suggested starting points. Titration of the Caspase-7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Amino acids 237-255 (RGSWFVQALCSILEEHGKD-human) were used as the immunogen for this Caspase-7 antibody.

Storage

After reconstitution, the Caspase-7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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