- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
c-Met Antibody / MET / HGFR [clone BFA-13] (RQ5243)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5243 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | BFA-13 |
| Purity | Affinity purified |
| UniProt | P08581 |
| Applications | Western blot : 1:500-1:2000 Immunohistochemistry (FFPE) : 1:50-1:200 Immunofluorescence : 1:50-1:200 |
| Limitations | This c-Met antibody is available for research use only. |
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This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. [RefSeq]
Optimal dilution of the c-Met antibody should be determined by the researcher.
A synthetic peptide specific to human c-Met / MET was used as the immunogen for the c-Met antibody.
Store the c-Met antibody at -20oC.
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