- Tel: 858.663.9055
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- Tel: 858.663.9055
- Email: info@nsjbio.com
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BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
Titration of the BRAF antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This BRAF antibody was produced from rabbits immunized with B-RAF recombinant protein.
Aliquot the BRAF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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