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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.
Titration of the Bid antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 39-68 from the mouse protein was used as the immunogen for this Bid antibody.
Aliquot the Bid antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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