• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> Bax Antibody

Bax Antibody (F40098)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image F40098-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40098-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
Bulk quote request
Bax antibody western blot analysis in HL-60 lysate
›
Bax antibody western blot analysis in HL-60 lysate
IHC analysis of FFPE human hepatocarcinoma stained with Bax antibody
Flow cytometric analysis of HepG2 cells using Bax antibody (green) compared to a negative control cell (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Western blot analysis of Bax antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the Bax gene.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q07812
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This Bax antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

  • Applications : IHC-P
    Reactivity : Human
    Recrabbitmono
  • Applications : FACS, IF, WB, IHC-P
    Reactivity : Human
    Citation  Citations(22)
  • Applications : WB, ELISA
    Reactivity : Human
  • Applications : FACS, IHC-P
    Reactivity : Human
  • Applications : FACS, IF, IHC-P, WB
    Reactivity : Human
    Citation  Citations(3)
  • Applications : IHC-P
    Reactivity : Human
  • Applications : WB, FACS, IHC-P
    Reactivity : Human, Mouse, Rat
  • Applications : WB, ELISA
    Reactivity : Human
  • Applications : WB, ELISA
    Reactivity : Human
    Pred. Reactivity : Mouse, Rat
  • Applications : WB, ELISA
    Reactivity : Human
  • Applications : WB, IHC-P, FACS
    Reactivity : Human, Mouse, Rat

Description

Bax belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.

Application Notes

Titration of the Bax antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 41-76 (BH3 domain) from the human protein was used as the immunogen for this Bax antibody.

Storage

Aliquot the Bax antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Related Products

   1.   View all Bax antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.